Q2 2026 pilot cohort — applications open

500 pages in. 2 pages out.

Unified Network for Molecular Insights & Reporting Intelligence

UNMIRI turns NGS genomic reports into a 2-page Actionable Insight — top 3 treatment recommendations, contraindications, and matching clinical trials. Clinical output is rendered by deterministic templates; every claim cited. Built for the oncologist's 15-minute consult.

HIPAA-ready · BAA-backed · Zero-retention LLM pipeline · US data residency

unmiri.com/dashboard

Actionable Insight

NSCLC Adenocarcinoma — Synthetic Patient

Synthetic data — demonstration only
1

Osimertinib (Tagrisso)

EGFR L858R — FDA-approved first-line

Level 1
2

Erlotinib + Ramucirumab

EGFR exon 19/21 — OncoKB Level 2A

Level 2A
3

Carboplatin + Pemetrexed

Co-mutation TP53 — consider platinum doublet

Level 2B

Contraindication flagged

PD-L1 <1% — checkpoint inhibitor monotherapy not indicated. Avoid pembrolizumab first-line.

Report stats

487

source pages ingested

2

pages delivered

1.4s

processing time

Clinical trial match

NCT05116866

MARIPOSA-2 · Phase III · EGFR-mutant NSCLC

QR

3M+

solid tumor NGS tests ordered annually in the US

487

average pages in a raw genomic report

2–4 hrs

a bioinformatician spends per complex NGS summary

Built for diagnostic labs like yours

Regional Pathology LabsIndependent Oncology LabsHospital-Owned Genomics CentersMid-Market Diagnostic Groups+ Recruiting PA/NJ pilots — Q2 2026
Northwestern University · April 2026
“AI outperforms human oncologists at NGS report summarization — on accuracy, completeness, and clinical relevance.”

The study compared structured AI summaries against manual physician interpretation of 200 solid-tumor NGS reports. The gap wasn't marginal. The bottleneck isn't the sequencer — it's the interpretation layer that sits between the data and the clinician.

Source: Northwestern Feinberg School of Medicine, April 2026

500 pages, no prioritization

Raw NGS outputs are dense by design — they're built for bioinformaticians, not oncologists making treatment calls in a 15-minute consult.

2–4 hours per complex case

Your bioinformatician is spending half a working day writing a manual summary that a competing lab is automating in seconds.

Revenue walks to Tempus

When oncologists can't get interpreted reports fast, complex cases go to Tempus or Foundation Medicine — and the billing follows. Your sequencing work funds your competitor.

The hard truth: “We sequence the tumor and hand it off — and Tempus gets the credit for the interpretation.”

— Common sentiment from regional lab directors

How it works

Three steps. Seconds to insight.

UNMIRI sits between your sequencer and the oncologist — translating genomic data into clinical action without touching your EHR.

01

Ingest

Raw NGS report arrives

Your LIMS sends the 500-page genomic report to UNMIRI via REST API. AWS Textract plus per-lab parsers convert it into structured variant JSON. No EHR integration required.

VCF · FHIR R4 · PDF · HL7

02

Analyze

Graph-based retrieval matches every variant

UNMIRI's knowledge graph — built on OncoKB, ClinVar, ClinicalTrials.gov, and openFDA drug labels — traverses variant → drug → evidence level → contraindication via deterministic Cypher queries. Same input, same output, every time.

OncoKB · ClinVar · ClinicalTrials.gov · openFDA

03

Deliver

Deterministic templates render the cheat sheet

The 2-page Actionable Insight is rendered by typed templates from structured graph output, not generated by an LLM. Every claim is cited. Templates can't hallucinate.

PDF · JSON · EHR-ready

The knowledge graph drives clinical reasoning. Deterministic templates render the output. LLMs are used narrowly — for extraction edge cases and long-tail variant fallback — and never in the clinical path itself.

Before & after

This is what your oncologists deal with today.

One delivers raw data. The other delivers a decision.

NGS_Report_PT_123456_FINAL.pdf (487 pages)
Today
EGFR exon 21 L858R pathogenic variant identified in tumor sample...
Variant allele frequency: 34.2% (read depth 847×)
TP53 R175H co-occurring variant identified (VAF 41.1%)...
TMB: 4.2 mut/Mb (low)
MSI status: MSI-Stable
PD-L1 TPS: <1% (Dako 22C3)
Copy number: EGFR amplification not detected
KRAS, NRAS, BRAF wild-type confirmed...
HER2 IHC 1+, FISH not amplified
ALK rearrangement: negative by IHC/FISH...
ROS1 rearrangement: negative by IHC...
MET exon 14 skipping: not detected
RET fusion: negative...
NTRK1/2/3 fusion: negative...
[continues for 487 more pages]

Oncologist still reading on page 12 of 487. Consult in 8 minutes.

UNMIRI Actionable Insight · PT-123456
2 pages

Top 3 Recommendations — Evidence-graded

1

Osimertinib (Tagrisso)

EGFR L858R · Level 1 · FDA-approved first-line

2

Erlotinib + Ramucirumab

EGFR exon 21 · OncoKB Level 2A · FDA-approved

3

Carboplatin + Pemetrexed

TP53 co-mutation · Level 2B · consider platinum doublet

Contraindication flagged

PD-L1 <1% — immunotherapy monotherapy not indicated. Avoid pembrolizumab first-line.

Matching clinical trial

NCT05116866 — MARIPOSA-2

Phase III · EGFR-mutant NSCLC · Enrolling

QR

Ready for the 15-minute consult. Synthetic data — demonstration only.

Who it's for

Built for the people who run regional diagnostic labs.

We're not selling to oncologists. We're selling to the labs that serve them — and we know exactly who reads the procurement docs.

Lab Director

Move up the value chain.

You're running one of the best NGS labs in the region. Your oncologist clients are getting 500-page PDFs. Tempus is calling them with interpreted reports. UNMIRI lets you offer what Tempus offers — without ceding your client relationships to do it.

Client retentionRevenue per testLab differentiation
See the economics →
Lab CTO / Bioinformatics Lead

An architecture you can defend.

The knowledge graph reasons over variants. Deterministic templates render the output. LLMs are used narrowly for extraction edge cases and long-tail fallback — never on the clinical path. REST API with full audit logging, US-only data residency, and a data-flow diagram you can put in front of your CAP inspector.

GraphRAGREST APIZero-retention
Review the architecture →
VP Operations / CFO

The math is straightforward.

$100 per report. A mid-size lab running 200 NGS panels/month spends $20K/month with UNMIRI — versus one bioinformatician at $120K/year or a single lost oncology client worth $500K–$2M in annual volume.

$100/reportNo headcountDays to integrate
Run the numbers →

Not a fit: academic medical centers with 10+ bioinformaticians, national labs (Tempus/Foundation-scale), or labs running fewer than 50 NGS panels/month.

Compliance & security

We can answer your security questionnaire today.

Most AI vendors go vague when procurement asks about PHI. We've built our compliance posture into the architecture — not bolted it on afterward.

HIPAA-ready

Designed for PHI from day one. BAA available on Enterprise tier. Every system component is evaluated against HIPAA Security Rule requirements before it touches patient data.

BAA available on request

Narrow LLM use, zero-retention

LLMs are scoped to extraction edge cases and long-tail variant fallback — never clinical reasoning. UNMIRI uses Anthropic's HIPAA-ready API tier with a signed BAA. No customer data is used for model training.

Anthropic HIPAA-ready API · zero-retention

US-only data residency

UNMIRI's architecture runs on HIPAA-covered tiers of Vercel and AWS pinned to US regions, with narrow LLM calls to Anthropic's HIPAA-ready API. PHI does not cross international borders. Data-flow diagram available on request.

Vercel · AWS · Anthropic (US-only)

BAA-backed subprocessors

UNMIRI's active BAA chain covers Vercel, AWS, and Anthropic — three subprocessors on the PHI path, each with a BAA on file. The full subprocessor list is published at /security/subprocessors and updated within 10 business days of any change.

Vercel · AWS · Anthropic

Encryption at rest & in transit

AES-256 at rest, TLS 1.3 in transit. Audit logging on all data access events. Role-based access controls with least-privilege enforcement across the entire pipeline.

AES-256 · TLS 1.3 · RBAC

SOC-2 Type II — roadmap

We're honest about stage: SOC-2 Type II audit is on our roadmap, target date TBD. In the meantime, we provide a full security review package including our controls documentation and infrastructure BAAs.

Honest placeholder — roadmap Q4 2026
Q2 2026 pilot cohort — applications open

Ready to offer interpreted NGS reports?

Pre-pilot. Onboarding 2–3 regional labs for retrospective pilots in the mid-Atlantic. We run a structured 30-day engagement: your NGS data, your LIMS workflow, your oncologist clients. You see the output before you commit. BAA and data-flow diagram ready for your legal team on day one.

No EHR integration required · LIMS REST API · BAA on request · US-only data residency