Trial index · Refreshed from ClinicalTrials.gov
Oncology trials by gene and variant
Browse active oncology clinical trials indexed by the genomic alteration they enroll on. Each page mirrors the underlying ClinicalTrials.gov listing with UNMIRI's variant-aware filtering. Updated nightly.
Beta: the live trial-by-gene pages are rolling out. Until each page lands, the link below routes to ClinicalTrials.gov directly with the appropriate search query.
- EGFR — EGFR-mutant NSCLC→
- KRAS G12C — KRAS G12C NSCLC→
- BRAF V600 — BRAF V600 melanoma→
- ALK — ALK-fusion NSCLC→
- ROS1 — ROS1-fusion NSCLC→
- MET exon 14 — MET exon 14 NSCLC→
- RET — RET-fusion NSCLC→
- NTRK — NTRK-fusion pan-tumor→
- HER2 — HER2-low breast→
- BRCA1/2 — BRCA1/2 ovarian→
- BRCA2 — BRCA metastatic prostate→
- IDH1/IDH2 — IDH AML→
- FLT3 — FLT3 AML→
- MSI-H — MSI-H pan-tumor→
- TMB-H — TMB-H pan-tumor→
- CDKN2A — CDKN2A loss pan-tumor→
Want trial-matching as an API?
The trial-matching capability is part of Engine 1. Vendor reports get trial matches in the FHIR Genomics output, with variant-aware filtering by indication, line of therapy, and prior treatment.
Related references
Pair each trial page with the underlying clinical decision-support reference in the variant cheat sheets or the dosing reference in the CPIC-aligned PGx pages.